Methylprednisolone therapy in tropical spastic paraparesis.

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Tropical spastic paraparesis.

Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases. We summarise our experience with the neuropathology of tropical spastic parapare...

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INTRODUCTION HTLV-1 infection is endemic in Japan, Caribbean, Africa, and South America. It is transmitted from mother to child, sexual contact, blood transfusions, or sharing needles. Tropical Spastic paraparesis (TSP) is a chronic degenerative neurological disease associated with this infection. It results from a spinal cord symmetrical degeneration at the thoracic level and is characterized ...

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Tropical spastic paraparesis from northern India.

In 1964, a progressive myelopathy involving the thoracic region was termed Tropical Spastic Paraparesis (TSP). Subsequently a similar myelopathy associated with HTLV-1 antibodies in both serum and CSF patients were found and named HAM (HTLV-1 associated myelopathy).1 The epidemiological, clinical and pathological features of cases from India are similar to the description form rest of World, th...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1990

ISSN: 0022-3050

DOI: 10.1136/jnnp.53.2.173-a